Uterine Rejuvenation
(PRP or Adipose-PRP)

They target completely different organs and solve different problems. Ovarian rejuvenation injects PRP or Adipose-PRP into the ovaries to improve egg production and quality — it's for women with low AMH, POI, or menopause who want to conceive with their own eggs. Uterine rejuvenation delivers PRP or Adipose-PRP into the uterine lining (endometrium) to improve thickness, receptivity, and blood flow — it's for women who have good embryos but struggle with implantation failure, recurrent miscarriage, thin lining, or uterine scarring. Some patients benefit from both procedures, and they can be performed together at RFC.

Yes. Women who have been told they cannot carry a pregnancy due to thin endometrium, recurrent implantation failure, or Asherman syndrome may be candidates for uterine rejuvenation as an alternative to surrogacy. PRP or Adipose-PRP can support endometrial repair and improve the uterine environment for implantation. RFC has helped women who were previously advised to use a gestational carrier achieve pregnancy after uterine rejuvenation. However, success depends on the severity of the uterine condition, and not all cases respond. Your physician will provide an honest assessment of whether carrying a pregnancy is realistic for your situation.

The two methods serve different clinical needs. PRP uterine infusion is simpler — PRP is gently placed into the uterine cavity through a thin catheter (similar to an embryo transfer), performed in the office without anesthesia, and its effects last for that one cycle. Hysteroscopic PRP injection is more targeted — PRP is injected directly into specific areas of the endometrial lining under camera guidance, requires sedation, and the effects can last up to 3 months. Your RFC doctor will recommend the method based on the severity of your condition, whether you have scarring or focal damage, and your upcoming embryo transfer timeline.

Timing depends on which method is used. For PRP uterine infusion, the effect begins within 24 hours and is specific to that cycle, so it is typically done shortly before the planned embryo transfer. For hysteroscopic PRP injection, the effects begin within a couple of weeks and can last up to 3 months, so it can be performed weeks in advance of the transfer cycle. For Adipose-PRP uterine injection, the effects may last up to 6 months. Your RFC physician will coordinate the timing to align rejuvenation with your embryo transfer schedule for the best possible outcome.

Uterine rejuvenation with PRP or Adipose-PRP is intended to support endometrial health, improve blood flow, and enhance receptivity — factors that play a role in both implantation and early pregnancy maintenance. For women experiencing recurrent chemical pregnancies or miscarriages linked to endometrial quality (rather than embryo genetics), uterine rejuvenation may help by creating a more supportive environment for the embryo to implant and develop. It is used as an adjunctive treatment alongside standard fertility care, not as a replacement. Your doctor will assess whether your pregnancy losses are likely related to uterine factors before recommending this approach.

Yes, uterine rejuvenation can be repeated. If a PRP infusion or injection does not produce sufficient endometrial improvement, your physician may recommend repeating the procedure, changing the method (for example, moving from infusion to hysteroscopic injection), or upgrading to Adipose-PRP for a stronger regenerative effect. Some patients require more than one treatment cycle to see meaningful improvement, particularly those with significant scarring or long-standing thin endometrium. If repeated attempts do not achieve adequate results, your doctor may discuss stem cell therapy options at RFC Bahamas.